Jeanne A. Hardy, Ph.D. is a structural biologist focused on identifying and exploiting new allosteric sites on proteases of biomedical interest. These allosteric sites are of general interest in and appear to be relevant to drug discovery, particularly in challenging targets. To date her laboratory has identified novel allosteric sites in four different proteases including caspase-6, -7, -9 and NSB2-NS3pro from dengue virus. Hardy was trained first as a chemist (BS/MS Chemistry, Utah State Univ. ’94) and later learned structural biology (Ph.D. Molecular & Cellular Biology, U.C. Berkeley ’00) under thesis advisor Hillary Nelson. In 2001 she joined the laboratory of James Wells at Sunesis Pharmaceuticals as a post-doctoral fellow. At Sunesis she participated in drug development first hand and became enamored of proteases. Hardy joined the faculty in the Department of Chemistry at the University of Massachusetts Amherst in 2005 and was subsequently selected as a Beckman Young Investigator and Cottrell Scholar. She was promoted to Associate Professor with tenure in 2012. In 2014 Hardy was awarded a Fulbright Fellowship for study at Pasteur Institute in Paris. Hardy is active in scientific publishing, serving on the editorial board of Biochemical Journal and the publications committee of ASBMB.